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The Dr. Rath Research Institute in Santa Clara, California was founded by Matthias Rath, MD, a researcher and medical doctor who made significant scientific breakthroughs in the area of natural health. His close friend, two-time Nobel Prize laureate and a pioneer in vitamin C research, the late Dr. Linus Pauling stated that Dr. Rath’s discoveries will be considered as the most important in the 20th Century.

The Dr. Rath Research Institute, led today by a long time associate of Dr. Rath, Dr. Aleksandra Niedzwiecki, PhD, has become a world leader in natural health science and the pioneer in developing micronutrient synergy-based health approaches.

Our researchers use state of the art scientific equipment and methodology to gain better insight into how natural substances work in our body’s cells and to develop and test the most effective combinations of natural substances that can benefit our health ...hide content

Our Achievements: Our Achievements:  For the first time in the history of medicine we provided clinical proof that heart disease can be stopped and even reversed by a natural program of micronutrients essential for maintaining healthy function of the blood vessel walls  We were the first to show that heart disease is not a high cholesterol problem, but the consequence of chronic deficiency of vitamin C and other micronutrients in the blood vessel walls  We were the first to develop a new approach effective in stopping the spread of cancer in the body. In more than 90 scientific publications we documented that a natural program comprising vitamins, amino acids, polyphenols and other essential nutrients can stop cancer metastasis – the deadliest stage of cancer. In addition, this program can halt the growth of tumors, and decrease the growth of blood vessels that feed the tumor and thus induce the natural death of cancer cells.  We were the first to introduce the “nutrient synergy” approach as the most effective and balanced way to maximize the health benefits of micronutrients. Our natural programs use carefully selected and scientifically tested combinations of micronutrients based on their synergistic effects. Our research was instrumental in documenting the benefits of micronutrients in AIDS and in unraveling the economic basis of the pharmaceutical business with AIDS. ( http://www.dr-rath-foundation.org The results of our community project in South Africa  documenting the benefits of  macronutrients in decreasing and halting the progression of AIDS in patients suffering from HIV/AIDS, http://www.dr-rath-foundation.org/nat_vit/index.html  , have been recently confirmed. ...hide content

Importance of Research and Public Education for the Future of Natural Health: Importance of Research and Public Education for the Future of Natural Health:  Research is the most effective tool in supporting the efficacy of natural approaches to health and enforcing the credibility of the entire natural health industry. Research is also the most powerful weapon in defending natural health against the attacks launched by its opponents. Our Research Institute is leading in public natural health education through innovative approaches such as interactive BodyXQ program, power point modules and recently launched Health Science News Page (HSNP) . All available online free of charge. ...hide content

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Maternal diet during pregnancy linked to healthy infant growth

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Clinical research studies and clinical trials have play a vital role in finding new and effective treatments. When you participate in a clinical research study aimed at treating mental illness, you are helping in finding better ways to prevent, detect or treat mental health conditions. You may receive free treatment or therapy and even be paid for your participation.  Read more about clinical research and current opportunities in the Bay Area.

About Mental Health Clinical Research and Studies

• *New* NAMI Research News
• Where to Find Clinical Research in the San Francisco Bay Area
• List of Current Studies

(Back to Top)

What is clinical research?

Clinical research refers to studies in which people participate as patients or volunteers. Different terms are used to describe clinical research, including clinical studies, clinical trials, studies, research, trials, and protocols. Clinical research may have a number of goals, such as developing new treatments or medications, identifying causes of illness, studying trends, or evaluating ways in which genetics may be related to an illness. The study volunteers can be people with diagnosed mental illness or healthy participants with no history of mental illness.

Strict rules for clinical studies have been put in place by NIH and the U.S. Food and Drug Administration (FDA). Some studies involve promising new treatments that may directly benefit participants. Others do not directly benefit participants, but may help scientists learn better ways to help people.

For more information refer to NIH Publication No. 08-4379 http://www.addrc.org/mental-health-clinical-trials/

Why Participate in Clinical Research?

Clinical research studies and clinical trials have play a vital role in finding new and effective treatments. When you participate in a clinical research study aimed at treating mental illness, you are helping in finding better ways to prevent, detect or treat mental health conditions.

Being part of clinical research gives you access to latest treatment options, medical examinations under the careful supervision of physicians and research team who are experts in that particular area of medicine. Some of the studies may also provide compensation for time and travel to the study to the research volunteers. Be aware that participating in the study does not ensure that you will receive the latest treatment. You could be part of the placebo group, or there may be unfavorable side-effects. However, since you are under the care of a dedicated team, you will be educated and quickly treated if there are any undesirable side-effects.

Choosing to take part in clinical research is an important personal decision. Your decision to participate will depend on your interests, needs, and expectations about research.

Confidentiality is an important part of clinical research and ensures that personal information is seen only by those authorized to have access. It also means that the personal identity and all medical information of clinical trial participants is known only to the individual patient and researchers. Results from a study will usually be presented only in terms of trends or overall findings and will not mention specific participants.

People sometimes think that participating in a study will require changes to their current treatment, but this is not always the case. Though some studies may require participants to try new medications or treatments, other studies use techniques such as brain scans, psychological tests, behavioral observation, or blood tests for genetic evaluation. Such studies may not require any change in treatment. (Back to Top)

Where to find Clinical Research in the San Francisco Bay Area

There are many opportunities to participate in clinical research in the San Francisco Bay Area. Some of the studies may also offer some compensation for participation. Below are links to some of the schools and institutions that have current clinical trials that are open and seeking volunteers.

• Stanford University
• Stanford Neurodevelopment, Affect, and Psychopathology Laboratory
• Stanford Yoon Lab Studies on Schizophrenia and Related Disorders
• Stanford Medicine Center for Interdisciplinary Brain Sciences Research
• University of California San Francisco
• University of California, Berkeley

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  List of Current Research Studies

Want to know how clinical research trials work?  The attached flyer from the National Institute of Mental Health lists questions and answers about these trials.

• About Clinical Research Trials

Stanford Clinical Research Study for Schizophrenia

People may experience schizophrenia in different ways based on their race, ethnicity, gender, age, and background. Having a diverse group of people in the study will help to see how the potential new drug works for different people.

Healthy Lifestyles for Bipolar Disorder

This is a clinical trial for adults with bipolar disorder who experience issues with sleep or daily routines. The trial will test whether two forms of healthy eating – Time-Restricted Eating (TRE) and the Mediterranean diet – can help reduce mood symptoms and improve quality of life.

Taking Action for Whole Health and Wellbeing Research Study

The Temple University Collaborative on Community Inclusion is looking to recruit participants for a paid research study on Taking Action for college students with mental health challenges. Taking Action is a peer-delivered group intervention that helps participants create a personalized system for improving and maintaining wellness and recovery.

Stanford PTSD Research Study

Stanford Psychiatry Center for Interdisciplinary Brain Sciences Research is looking for participants for two studies. 1. PTSD Social support study 2. PTSD Brain biomarker study

Mental Health & Substance Use Services Survey

The Behavioral Health Services Department is gathering feedback from people who live in Santa Clara County, have utilized either mental health or substance use services, or have feedback on what services are needed. Please share your input in a confidential and anonymous survey administered between August and September 2024.

Sleep Treatment Needs of Caregiving Family Members for Adults with Serious Mental Illness

The aim of this study is to inform how behavioral sleep treatments can be adapted to better meet the needs of family caregivers who experience sleep challenges while providing support to a family member with serious mental illness.

Temple University – Research Study on Community Participation

Temple University Collaborative On Community Inclusion of Individuals with Psychiatric Disabilities, CONNECTIONSRX, is a technology-based, distance intervention aimed to increase community participation of emerging adults (18-30 years old) with serious mental illnesses.

Stanford Research- Ketamine’s Rapid Effects in OCD

Rodriguez lab, Translational Therapeutics of Stanford University, Stanford School of Medicine, is currently looking for participants with Obsessive Compulsive Disorder, ages 18 – 65 years for their research on “Examining Mu Opioid Mechanisms of Ketamine’s Rapid Effects in Obsessive Compulsive Disorder”.

Resources and Programs for Youth Under Age 14

This is an online survey for NAMI State Organization (NSO) and NAMI Affiliate (NA) staff and volunteers to help the National Office learn about resources and programs for youth under age 14 currently offered by the Field. NAMI also welcomes information about why NSO/NAs have chosen to offer or not offer these resources and programs.

Stanford Clinical TMS Study for OCD

Brain Stimulation Lab at Stanford University, Department of Psychiatry and Behavioral Sciences, is currently looking for participants with Obsessive Compulsive Disorder (OCD) for our 5-day accelerated Transcranial Magnetic Stimulation (TMS) study.

Stanford Neurodiversity Research Study

Stanford Neurodiversity Project – Join the research in developing culturally sensitive CBT therapy for Autistic Chinese Adolescent and Young Adults!

Bolster Mobile App Research for Caregivers of Young Adults

University of Washington has developed Bolster – a mobile app designed to support caregivers of young adults with early psychosis. The Bolster app aims to support caregivers who are trying to help facilitate their loved one’s access to care, and thus aims to reduce duration of untreated illness. At this stage, we are looking to…

Stanford Yoon Lab Schizophrenia PET Scan Research Study

The Yoon Lab is conducting a positron emission tomography (PET) neuroimaging study in individuals with schizophrenia and related disorders ages 18-55.

NAMI Research – Role of Creativity on Young People’s Lives

NAMI is seeking the perspectives of individuals who work with young people on a regular basis to better understand the role of creativity in young people’s lives. In collaboration with an industry partner, NAMI is conducting a brief survey to learn more about the benefits and drawbacks of creativity, as well as what factors make…

Neuroimaging of Trauma (NeT) Research Study

The Neuroimaging of Trauma (NeT) study uses neuroimaging to understand more about how exposure to traumatic experiences in early adulthood affects the brain. Participants will be asked to come to the San Francisco VA Medical Center for several research tests, including a psychological interview, blood tests, and an MRI of the brain on 4 separate days, over the course of two weeks to 1 month. 

NAMI Research Opportunity – Survey for adults with schizophrenia and/or their caregivers

This study is seeking input via online survey from people with schizophrenia and caregivers of those with schizophrenia.   The survey will ask questions about what it is like to live with schizophrenia, participant experiences with medications and other ways of managing symptoms, and what people want to see from future drug treatments. The goal…

The Ethics of Digital Mental Health Technology

The aim of the study is to learn more about the perspectives of mental health consumers on ethical issues, such as concerns about privacy or data protection related to the use of digital mental health. To participate in the study, you must be: 18+ years of age You have used or strongly considered using apps…

Stanford University Teen Health Study: Investigating Risk Factors of Eating Disorders

Stanford University research group is conducting a teen health study that is investigating factors that predict healthy adolescent development and eating behaviors. The results of the study will be used to inform future eating disorder prevention programs.       To participate in the study, you must be: The parent of a daughter 13 – 15…

UC Berkeley CALM Program Study: Understanding Suicide Attempts

The CALM Program at UC Berkeley is conducting a study of thoughts, motivation, and self-control among people who have attempted suicide in the past 5 years. To participate in the study, you must be: Between the ages of 18-55 years old Able to come to UC Berkeley campus for up to four 1-3 hour visits…

University of Washington – Bolster Project Seeking Participants Caregivers to a Young Adult

This study is for caregivers of young people (age 15-35) with psychosis who are interested in providing input into the design of a caregiver-facing mobile mental health (mHealth) platform.

Online Survey – Treatment Access in Schizophrenia or Schizoaffective

RESEARCH OPPORTUNITY NAMI is committed to ensuring that the most effective treatments for mental illness are available to those who need them. Determining which treatments are most effective requires research. When NAMI is approached to be involved in research of any type, at any level, we take it very seriously. NAMI’s Chief Medical Officer Dr.…

Online Survey – Testing a Model of Recovery from Schizophrenia

This study is an online survey for individuals with schizophrenia or schizoaffective disorder. The goal of this study is to understand the personal experiences and characteristics associated with recovery in schizophrenia/schizoaffective disorder.

Online Survey – On Long Acting Injectable Medications (individuals and caregiver survey)

This study is an online survey for adults with psychosis and their caregivers. The goal of this study is to understand the experiences of individuals currently being treated with a long-acting injectable medication and their caregivers.

Schizophrenia fMRI Research Study

Stanford Yoon Lab study utilizing fMRI to discover the brain circuits responsible for schizophrenia and translating this knowledge into the clinic to improve how we diagnose and treat this condition.

Schizophrenia and the Immune System Research Study

Stanford University and Inspire Clinic are studying the immune system in the disease process of schizophrenia.

Are You Angy? Behavior and Mental Health Research Study

Our research group in the Psychology Department at UC Berkeley is conducting a study to examine how different thoughts, behaviors, and emotions are related to decision making and psychological symptoms. We are currently seeking folks who have thrown things, hit someone, yelled, or are recovering from prior substance abuse.

Stanford Teen Mood Research Study

The Stanford Neurodevelopment, Affect, and Psychopathology (SNAP) Lab is looking at how mood affects the brain and body. More specifically, patterns between biomarkers (like markers of stress/inflammation in the brain and blood such as cortisol, cytokines and brain functioning) and depressive symptoms in adolescents.

Stanford Research Study for People With Social Anxiety

Do you get anxious in social situations? You’re not alone. Social anxiety disorder affects as many as 12% of Americans, and can result in significant distress and disability. Cognitive behavior therapy is one of the best treatments available, but as many as 25% of patients do not fully respond and we do not know why. This…

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Our discoveries improve people’s lives. In doing so, they improve the world.

Across University of California Health (UCH), the world’s top researchers work together to solve the toughest problems facing humanity.

They’re building on a strong track record of leading-edge, data-driven discovery. Researchers at UCH and the University of California (UC) have helped invent CRISPR/Cas9 gene editing, the nicotine patch, the vaccine for hepatitis B, drugs to treat prostate cancer, and much, much more. Their discoveries improve health and well-being across all of California’s — and many of the world’s — populations. And these innovations directly shape care at UCH’s six academic health centers .

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Nih research matters.

December 18, 2024

2024 NIH Research Highlights - Basic Research Insights

Noteworthy advances in fundamental research.

With NIH support, scientists across the United States and around the world conduct wide-ranging research to discover ways to meet the NIH mission to enhance health, lengthen life, and reduce illness and disability. Groundbreaking NIH-funded research often receives top scientific honors. In 2024, these honors included  three NIH-supported scientists who received Nobel Prizes . Here’s just a small sample of the NIH-supported research accomplishments in 2024. Also see this year's  Human Health Advances and Promising Medical Findings .

Printer-friendly version of full 2024 NIH Research Highlights

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H5N1 avian influenza transmission

Researchers gained insights into whether the H5N1 flu outbreak in cows could lead to a human pandemic. H5N1 survived in raw dairy milk kept under refrigerated conditions for at least five weeks. When mice consumed infected raw milk, they showed signs of illness. This suggests that drinking raw milk may pose a risk for people. But pasteurization-like treatment significantly reduced levels of the virus. An H5N1 virus taken from cows was able to infect mice and ferrets , but airborne transmission wasn’t very efficient. Another H5N1 virus, from an infected farm worker , could transmit through airborne droplets and was lethal in mice and ferrets. The findings emphasize the risks from the current outbreak and the need for continued monitoring and testing.

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Why protective antibodies fade after COVID-19 vaccines

Mature and durable antibody-producing cells are key to providing long-lasting immunity against infection. Researchers looked in the bone marrow of healthy, vaccinated adults and found such cells targeting tetanus and influenza, but not SARS-CoV-2. The findings could help explain why protection from COVID-19 vaccines tends to decline over time. A better understanding of how these long-lived immune cells are formed could lead to improved vaccines that provide enduring protection.

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Mapping how cancers form and spread

3D maps of cancer from an NIH initiative provided critical information about how tumors develop, spread, and respond to treatments. Researchers were able to identify distinct substructures, called microregions, within many tumors. Cells in different microregions often behaved differently. These maps provide a better understanding of the development and progression of cancer. This could eventually lead to new prevention and treatment strategies.

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Understanding how exercise affects the body

Exercise is one of the most beneficial activities that people can engage in. But exactly how exercise exerts its positive effects hasn’t been well understood. A study of endurance training in rats found molecular changes throughout the body that could help explain the beneficial effects of exercise on health. Large differences were seen between male and female rats, highlighting the need to include both women and men in exercise studies.

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Advances in understanding the brain

Scientists generated a high-resolution map of all the cells and connections in a single cubic millimeter of the human brain . The map revealed details of brain structure never seen before. Other researchers fully mapped the connections between neurons for an entire adult fruit fly brain . This map is a stepping stone to creating whole brain maps in larger animals. Both maps can improve our understanding of brain function and provide resources for further studies. Researchers also created massive, advanced maps of the complex networks that regulate gene function in the brains of people with and without mental disorders. Their findings offer new insights into how gene activities affect the brain, which could lead to improved treatments for mental health conditions.

2024 NIH Research Highlights - Human Health Advances

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